Since their discovery in 1993, small non-coding RNAs (microRNAs, scaRNAs, and snoRNAs) have emerged as major components in the regulatory circuitry that underlies the development and physiology of complex organisms.
As a result, it is becoming increasingly important to complement messenger RNA (mRNA) gene expression studies with miRNA analysis to understand the biological context of differentially expressed genes. These key functional gene products are estimated to regulate approximately 30 percent of all protein-coding genes.
GeneChip® miRNA Arrays are powerful tools for studying the role of small non-coding RNA (microRNAs or miRNAs) and their importance in cancer and other diseases.
